Check out our current research as well as previous research published by Dr. Hartley during her PhD and postdoc!
Current Publications
- Lipidomic analysis reveals differences in the extent of remyelination in the brain and spinal cord. https://doi.org/10.1101/2023.07.24.550351
Dr. Hartley’s Postdoc Publications
- Pharmacological Complementation Remedies an Inborn Error of Lipid Metabolism. Cell Chemical Biology.
May 2020. https://doi.org/10.1016/j.chembiol.2020.02.008
- Myelin repair stimulated by CNS-selective thyroid hormone action. JCI Insight. April 2019. https://doi.org/10.1172/jci.insight.126329
- Sobetirome and its Amide Prodrug Sob-AM2 Exert Thyromimetic Actions in Mct8-Deficient Brain. Thyroid. June 2018. https://doi.org/10.1089/thy.2018.0008
- A Thyroid Hormone-Based Strategy for Correcting the Biochemical Abnormality in X-Linked Adrenoleukodystrophy. Endocrinology. May 2017. https://doi.org/10.1210/en.2016-1842
- Ester-to-amide rearrangement of ethanolamine-derived prodrugs of sobetirome with increased blood-brain barrier penetration. Bioorganic & Medicinal Chemistry. May 2017. https://doi.org/10.1016/j.bmc.2017.03.047
- Sobetirome prodrug esters with enhanced blood-brain barrier permeability. Bioorganic & Medicinal Chemistry. Nov 2016. https://doi.org/10.1016/j.bmc.2016.09.038
- Remyelination and multiple sclerosis: therapeutic approaches and challenges. Current Neurology and Neuroscience Reports. Aug 2014. https://doi.org/10.1007/s11910-014-0485-1
Dr. Hartley’s PhD Publications
- Lipid bilayer nanodisc platform for investigating polyprenol-dependent enzyme interactions and activities. PNAS. Dec 2013. https://doi.org/10.1073/pnas.1320852110
- At the membrane frontier: a prospectus on the remarkable evolutionary conservation of polyprenols and polyprenyl-phosphates. Archives of Biochemistry and Biophysics. Jan 2012. https://doi.org/10.1016/j.abb.2011.10.018
- Biochemical characterization of the O-linked glycosylation pathway in Neisseria gonorrhoeae responsible for biosynthesis of protein glycans containing N,N’-diacetylbacillosamine. Biochemistry. Mar 2011. https://doi.org/10.1021/bi2003372
- Genetic and molecular analyses reveal an evolutionary trajectory for glycan synthesis in a bacterial protein glycosylation system. PNAS. May 2011. https://doi.org/10.1073/pnas.1103321108
- Chemoenzymatic synthesis of polyprenyl phosphates. Bioorganic & Medicinal Chemistry. Mar 2008. https://doi.org/10.1016/j.bmc.2008.03.025